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Image Search Results
Journal: bioRxiv
Article Title: A genetic and physiological model of renal dysfunction in Lowe syndrome
doi: 10.1101/2024.01.15.575703
Figure Lengend Snippet: (A) Confocal micrographs of 10KDa TMR-dextran uptake assay in control, dOCRL KO and dOCRL KO ;hs>HA::dOCRL. (B) Mean fluorescence intensity (MFI) of 10KDa TMR-Dextran in nephrocytes per unit area calculated using imageJ. (C) Confocal micrographs of mBSA-Cy5 uptake assay in control, dOCRL KO and dOCRL KO ;hs>HA::dOCRL. (D) Quantification of uptake of mBSA by calculating the MFI. (E-F) Confocal micrographs and quantification of Immunostaining of control, dOCRL KO nephrocytes with early endosome marker EEA-1, nucleus of these cells was stained with DAPI. (G) Confocal micrographs of nephrocytes labelled with 2XFYVE domain. UAS-mCherry::2XFYVE is driven in nephrocytes using Dot Gal4. (H) Quantification of MFI of mCherry::2XFYVE by Imagej. Statistical tests: XY plots with mean ± S.E.M are represented. Two tailed unpaired t-test is used. ****p<0.0001, ***p<0.001, **p<0.01.
Article Snippet: mBSA was synthesized and conjugated with
Techniques: Fluorescence, Immunostaining, Marker, Staining, Two Tailed Test
Journal: Lipids in Health and Disease
Article Title: Ergothioneine ameliorates metabolic dysfunction-Associated Steatotic Liver Disease (MASLD) by enhancing autophagy, inhibiting oxidative damage and inflammation
doi: 10.1186/s12944-024-02382-9
Figure Lengend Snippet: Ergothioneine ameliorated hepatic structural damage, hyperlipidemia, oxidative damage, and inflammation in HFD mice. ( A ) HE, PAS, Oil Red, and IHC (F4/80) staining. Bar = 100 μm. Serum levels of TG ( B ), TC ( C ), LDL-C ( D ) and HDL-C ( E ) in mice. ELISA kits detected serum levels of SOD ( F ), CAT ( G ), GSH ( H ), MDA ( I ), IL-1β ( J ) and IL-6 ( K ) in mice. n = 5. ** P < 0.01, *** P < 0.001, **** P < 0.0001 HFD vs. NCD; # P < 0.05, ## P < 0.01, ### P < 0.001, #### P < 0.0001 HFD + EGT vs. HFD
Article Snippet:
Techniques: Staining, Enzyme-linked Immunosorbent Assay